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KMID : 0371320070730050430
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Journal of the Korean Surgical Society
2007 Volume.73 No. 5 p.430 ~ p.433
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Malignant Adenomyoepithelioma of the Breast
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Park Min-Ho
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Abstract
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An adenomyoepithelioma of the breast is an uncommon tumor that is characterized by biphasic lesions, which consist of epithelial and myoepithelial cells. Most adenomyoepitheliomas are benign, and a malignant transformation is rare. It is generally limited to the epithelial component but in rare cases, the myoepithelial component may become malignant and give rise to a malignant myoepithelioma. We encountered a case of a 29-year-old woman who presented with both an epithelial and myoepithelial carcinoma of the breast in an adenomyoepithelioma. The malignancy was evidenced by the presence of pleomorphism, a high mitotic rate and local invasion. Immunohistochemical staining demonstrated the expression of cytokeratin in epithelial cells and actin in myoepithelial cells. We report this case of a malignant adenomyoepithelioma of the breast with review of the relevant literature. (J Korean Surg Soc 2007;73:430-433)
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KEYWORD
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Breast, Malignant, Adenomyoepithelioma
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